+ General Considerations

  • Uterine tumors are rare and account for 0.2%-1.5% of all feline tumors
  • Uterine ADC is more common in cats and arises from the endometrium (= endometrial carcinoma)
  • Metastatic sites include cerebrum, eye, ovary, adrenal glands, lungs, liver, kidney, bladder, colon, diaphragm, and regional lymph nodes
  • Other uterine tumors include leiomyoma, leiomyosarcoma, FSA, LSA, fibroma, and lipoma


+ Clinical Signs

  • Middle-aged to older animals
  • Abdominal enlargement with palpable abdominal mass
  • Vaginal discharge is common and can vary from purulent to mucoid to darkly hemorrhagic
  • Other signs include abnormal estrous cycles, polyuria-polydipsia, vomiting, and abdominal distension

+ Diagnosis

  • Abdominal palpation
  • Survey radiographs and ultrasonography to confirm origin of mass
  • Histopathology

+ Treatment

  • Ovariohysterectomy
  • Role and effectiveness of chemotherapy and radiation therapy is unknown

+ Prognosis

  • Surgical excision is curative for leiomyoma and other benign lesions
  • Prognosis is good for leiomyosarcoma and other malignant tumors if surgical excision is complete and there is no evidence of metastatic disease
  • Prognosis is guarded for feline endometrial carcinoma due to metastatic potential