Clinical trials and collaborative research in surgical oncology are actively encouraged by the VSSO. Prospective clinical trials are preferred, but multi-institutional retrospective case series will also be strongly considered. Research projects can include, but are not limited to, the study of new surgical techniques, multimodality treatment protocols, novel adjuvant agents, and treatment outcomes for different tumor types.


 

Research Proposal Submission

Requests for more information and proposal submissions can be directed to Dr. Michelle Oblak, Chairperson of the VSSO Research Committee,
by clicking on the link below.


 

OPEN RESEARCH TRIALS

2018-

UPDATE COMING SOON


 

Closed RESEARCH TRIALS 

•  Outcomes and prognostic variables for dogs with visceral soft tissue sarcomas

Principle investigator: Dr. Dan Linden and Dr. Brad Matz

Linden D, Liptak JM, Vinayak A, Grimes JA, Sandey M, Smiley W, Matz BM. Outcomes and prognostic variables associated with primary abdominal visceral soft tissue sarcomas in dogs: A Veterinary Society of Surgical Oncology retrospective study.Vet Comp Oncol. 2019 Jan 21

https://doi.org/10.1111/vco.12456

•  Post-Surgical Outcome in dogs with gastric carcinoma

Principle investigator: Dr. Vincent Wavreille

Abrams B, Wavreille VA, Husbands BD, Matz BM, Massari F, Liptak JM, Cray MT, de Mello Souza CH, Wustefeld-Janssens BG, Oblak ML, Su L, Selmic L.Perioperative complications and outcome after surgery for treatment of gastric carcinoma in dogs: A Veterinary Society of Surgical Oncology retrospective study of 40 cases (2004-2018). Veterinary Surgery. 2019 May 29.

https://doi.org/10.1111/vsu.13239

2017


•  Clinical findings, treatment and outcome in cats with sex-hormone secreting adrenal tumors leading to behavioral changes.

Principle investigator: Dr. Julia Sumner

Sumner JP, Hulsebosch SE, Dudley RM, Miller ML, Hayes GM. Sex-hormone producing adrenal tumors causing behavioral changes as the sole clinical sign in 3 cats. Canadian Veterinary Journal. 2019 Mar;60(3):305-310.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380267/

•  Total prostatectomy for the treatment of primary prostatic neoplasia in the dog.

Principle investigator: Dr. Tristram Bennett

Bennett TC, Matz BM, Henderson RA, Straw RC, Liptak JM, Selmic LE, Collivignarelli F, Buracco P.Total prostatectomy as a treatment for prostatic carcinoma in 25 dogs. Veterinary Surgery, 2018 Apr;47(3):367-377.

https://doi.org/10.1111/vsu.12768

2016


•  Assessment of survival advantage in dogs experiencing post-surgical infection following amputation for appendicular osteosarcoma

Principle investigator: Dr. Robert Dudley

Hans EC, Pinard C, van Nimwegen SA, Kirpensteijn J, Singh A, MacEachern S, Naber S, Dudley RM. Effect of surgical site infection on survival after limb amputation in the curative-intent treatment of canine appendicular osteosarcoma: a Veterinary Society of Surgical Oncology retrospective study.Veterinary Surgery, 2018 Nov;47(8):E88-E96

https://doi.org/10.1111/vsu.13105

2015


•   Retrospective evaluation of surgical technique, complications and outcome associated with pneumonectomy in veterinary surgery

Principle investigator: Dr. Sarah Boston

Wavreille, V., Boston, S. E., Souza, C., Ham, K., Chanoit, G., Rossetti, D., Takacs, J. and Milner, R. (2016), Outcome After Pneumonectomy in 17 Dogs and 10 Cats: A Veterinary Society of Surgical Oncology Case Series. Veterinary Surgery, 45: 782–78

https://doi.org/10.1111/vsu.12517

•   Retrospective evaluation of histopathologic results of medial retropharyngeal and mandibular lymph node extirpation for tumors of the head

Principle investigator: Dr. Janet Grimes

Grimes JA, Mestrinho LA, Berg J, Cass S, Oblak ML, Murphy S, Amsellem PM, Brown P, Hamaide A, Matz BM. Histologic evaluation of mandibular and medial retropharyngeal lymph nodes during staging of oral malignant melanoma and squamous cell carcinoma in dogs. JAVMA 2019 Apr 15;254(8):938-943

https://doi.org/10.2460/javma.254.8.938

•   Endoprosthesis

Principle investigator: Dr. Katherine Mitchell

Mitchell, K. E., Boston, S. E., Kung, M., Dry, S., Straw, R. C., Ehrhart, N. P. and Ryan, S. D. (2016), Outcomes of Limb-Sparing Surgery Using Two Generations of Metal Endoprosthesis in 45 Dogs With Distal Radial Osteosarcoma. A Veterinary Society of Surgical Oncology Retrospective Study. Veterinary Surgery 45: 36–43

https://doi.org/10.1111/vsu.12423

2014


2013

•   Rectal tumor surgery

         Principal investigator: Dr. Julius M. Liptak

Nucci DJ, Liptak JM, Selmic LE, Culp WTN, Durant AM, Worley D, Maritato KC, Thomson M, Annoni M, Singh A, Matz B, Benson J, Buracco P. Complications and outcomes following rectal pull-through surgery in dogs with rectal masses: 74 cases (2000-2013). JAVMA 2014;245:684-695

https://doi.org/10.2460/javma.245.6.684


2012

•   Dogs with apocrine gland anal sac adenocarcinoma: effect of sublumbar lymph node metastasis on prognosis.

             Principal investigator: Dr. Julius M. Liptak

Data analysis phase

•   Osteosarcoma following tibial plateau leveling osteotomy in dogs

            Principal investigator: Dr. Laura Selmic

Selmic LE, Ryan SD, Boston SE, Liptak JM, Culp WTN, Sartor AJ, Prpich CY, Withrow SJ. Osteosarcoma following tibial plateau leveling osteotomy in dogs: 29 cases (1997-2011). JAVMA 2014;244:1053-1059.

https://doi.org/10.2460/javma.244.9.1053


•   The surgical treatment of canine splenic lymphoma

            Principal investigator: Dr. Sarah Boston

van Stee LL, Boston SE, Singh A, Romanelli G, Rubio-Guzman A, Scase TJ. Outcome and Prognostic Factors for Canine Splenic Lymphoma Treated by Splenectomy (1995-2011).

•   Canine primary appendicular hemangiosarcoma. Veterinary Surgery. 2015 Nov;44(8):976-82.

https://doi.org/10.1111/vsu.12405

            Principal investigator: Dr. Michelle Giuffrida

Giuffrida MA, Kamstock DA, Selmic LE, Pass W, Szivek A, Mison MB, Boston SE, Fox LE, Robat C, Grimes JA, Maritato KC, Bacon NJ. Primary appendicular hemangiosarcoma and telangiectatic osteosarcoma in 70 dogs: A Veterinary Society of Surgical Oncology retrospective study. Veterinary Surgery. 2018 Aug;47(6):774-783

https://doi.org/10.1111/vsu.12926

2011


•   Evaluation of scapulectomy for primary bone tumors in dogs

          Principal investigator: Dr. Sarah Boston

Montinaro V, Boston SE, Buracco P, Culp WTN, Romanelli G, Straw R, Ryan S. Evaluation of scapulectomy for primary bone tumors in 42 dogs. Veterinary Surgery 2013

https://doi.org/10.1111/j.1532-950X.2013.12066.x

•   Appendicular osteosarcoma in dogs weighing less than 15kg

          Principal investigator: Dr. Pierre Amsellem

Amsellem PM, Selmic LE, Wypij JM, Bacon NJ, Culp WTN, Ehrhart NP, Powers BE, Stryhn H, Farese JP. Appenidcular osteosarcoma in small-breed dogs: 51 cases (1986-2011). JAVMA 2014;245:203-210.

https://doi.org/10.2460/javma.245.2.203

•   Retrospective review of splenic liposarcoma in dogs

            Principal investigator: Dr. Julius Liptak

Gower KL, Liptak JM, Culp WT, Bravo L, Powers B, Withrow SJ. Splenic liposarcoma in dogs: 13 cases (2002-2012). JAVMA. 2015 Dec 15;247(12):1404-7.

https://doi.org/10.2460/javma.247.12.1404

2010  


•   Retrospective evaluation of dogs with tumor-related pathologic fracture treated with fracture fixation

          Principal investigator: Dr. Sarah Boston

Boston SE, Bacon NJ, Culp WT, Bhandal J, Bruce C, Cavanaugh RP, Hamilton MH, Lincoln JD, Liptak JM, Scharvogel S. (2011). Outcome after repair of a sarcoma-related pathologic fracture in dogs: a veterinary society of surgical oncology retrospective study. Veterinary Surgery 2011;40:431-437.

https://doi.org/10.1111/j.1532-950X.2011.00820.x

•   Outcome following hemipelvectomy in the dog and cats

Principal investigator: Dr. Jonathan Bray, Massey University, New Zealand

Bray JP, Worley DR, Henderson RA, et al: Hemipelvectomy: outcome in 84 dogs and 16 cats. A Veterinary Society of Surgical Oncology retrospective study. Veterinary Surgery 2014;43:27–37

https://doi.org/10.1111/j.1532-950X.2013.12080.x

•    Retrospective evaluation of canine tongue tumors: results of surgical excision

          Principal investigator: Dr. William Culp

Culp WTN, Ehrhart N, Withrow SJ, Rebhun RB, Boston S, Buracco P, Reiter AM, Schallberger SP, Aldridge CF, Kent MS, Mayhew PD, Brown DC. Results of surgical excision and evaluation of factors associated with survival time in dogs with lingual neoplasia: 97 cases (1995-2008). JAVMA 2013; 242:1392-1397.

https://doi.org/10.2460/javma.242.10.1392

2009  


•    Retrospective review of apocrine gland anal sac adenocarcinomas in cats

           Principal investigator: Dr. Ryan Cavanaugh

Amsellem PM. Cavanaugh RP, Chou P, Bacon NJ, Schallberger SP, Farese JP, Kuntz CA, Liptak JM, Culp WTN, Robot CS, Powers BE. Apocrine gland anal sac adenocarcinoma in cats: 30 cases (1994-2015) JAVMA. 2019. 254(6):716-722

https://doi.org/10.2460/javma.254.6.716

2008  


•    Retrospective review of primary appendicular chondrosarcoma in dogs

          Principal investigator: Dr. Jim Farese

Farese JP., Kirpensteijn J, Kik M, Bacon NJ, Waltman SS, Seguin B, Kent M, Liptak J, Straw R, Chang MN, Jiang Y, Withrow SJ. Biologic behavior and clinical outcome of 25 dogs with canine appendicular chondrosarcoma treated by amputation: a Veterinary Society of Surgical Oncology retrospective study. Veterinary Surgery 2009;38:914-919.

https://doi.org/10.1111/j.1532-950X.2009.00606.x

2006   


VCS Clinical Trials

The Veterinary Cancer Society has established a webpage dedicated to Clinical Trials. This page addresses many questions concerning clinical trials and is an excellent source for those searching for treatment for their pet. Additionally, active clinical trials can be found at that site.