+ General Considerations
- Apocrine sweat gland tumors are more common as eccrine sweat glands only occur in the footpads
- Apocrine glands are numerous throughout the body and they are subclassified according to their location
- Sweat gland tumors account for 3.6%-9.0% of feline skin tumors and 2.0% of canine skin tumors
- ADC (50%-90%) is more common than adenoma
+ Sweat Gland Cysts
- Common and contain serous material
- Site: head
+ Sweat Gland Adenomas
- Mean age > 8 years
- Sex predisposition: male
- Breed predisposition: Cocker Spaniel
- Gross appearance: cystic with minimal inflammation and no ulceration in cats, and solitary, well-circumscribed, and slow growing with ulceration common (> 50%) in dogs
- 25% have evidence of lymphatic infiltration
- Sites: head and neck
- Treatment: surgery
- Prognosis: good
Sweat Gland Adenocarcinoma
+ Feline Sweat Gland Adenocarcinoma
- Mean age > 12 years in cats
- Sites: head
- Prognosis: guarded with metastasis reported to regional lymph nodes, digits, liver, and lung
+ Canine Sweat Gland Adenocarcinoma
- Mean age > 8 years in dogs
- Breed predisposition: Golden Retriever
- Sites: back, flank, and feet in dogs
- Prognosis: guarded to good in dogs with 8.3% local tumor recurrence rate and metastasis rare