GENERAL CONSIDERATIONS
+ Biologic Behavior
- Oral OSA is the 4th most common oral tumor in dogs and accounts for 6%-18% of oral tumors
- OSA is more common in appendicular skeleton with only 25.4% in the axial skeleton
- Mandibular OSA accounts for 27% of axial OSA (and < 4% of all OSA cases)
- Axial OSA, and mandibular OSA in particular, may have a lower metastatic rate than appendicular OSA
TREATMENT
+Surgery
Surgical techniques: mandibulectomy and maxillectomy
+Surgery and Radiopharmaceuticals
Samarium has been used following partial maxillectomy and local recurrence with survival times > 21 months
+Prognosis
- 12-month survival rate 59%
- 12-month survival rate with combinations of surgery, radiation therapy, and chemotherapy: 35%-59%
- MST for mandibulectomy is 14-18 months with 12-month survival rate 35%-71%, local recurrence rate 15%-28%, and metastatic rate 28%
- MST for maxillectomy is 4.6-10 months with 12-month survival rate 17%-27% and recurrence rate 33%
- Poor prognostic factor: high histologic grade for mandibular OSA treated with mandibulectomy