+ General Considerations
- Synonyms: rodent ulcer and indolent ulcer
- Eosinophilic granuloma is most common in female cats with a mean age of 5 years
- Etiology unknown
- Location: upper lip near midline is most common but can occur anywhere in the oral cavity
- Slowly progressive (months to years) erosion of the lip
- Biopsy required to differentiate from oral cancers
- Treatment: prednisone (1-2 mg/kg q 12 hours for 30 days), methylprednisolone acetate (20 mg SC q 2 weeks), megestrol acetate, hypoallergenic diets, radiation therapy, surgery, immunomodulation, or cryosurgery
- Prognosis: fair for complete and permanent recovery