+ General Considerations

  • Synonyms: rodent ulcer and indolent ulcer
  • Eosinophilic granuloma is most common in female cats with a mean age of 5 years
  • Etiology unknown
  • Location: upper lip near midline is most common but can occur anywhere in the oral cavity
  • Slowly progressive (months to years) erosion of the lip
  • Biopsy required to differentiate from oral cancers
  • Treatment: prednisone (1-2 mg/kg q 12 hours for 30 days), methylprednisolone acetate (20 mg SC q 2 weeks), megestrol acetate, hypoallergenic diets, radiation therapy, surgery, immunomodulation, or cryosurgery
  • Prognosis: fair for complete and permanent recovery