Veterinary Society of
Surgical Oncology

General Considerations

  • synonyms: rodent ulcer and indolent ulcer
  • eosinophilic granuloma is most common in female cats with a mean age of 5 years
  • etiology unknown
  • location: upper lip near midline is most common but can occur anywhere in the oral cavity
  • slowly progressive (months to years) erosion of the lip
  • biopsy required to differentiate from oral cancers
  • treatment: prednisone (1-2 mg/kg q 12 hours for 30 days), methylprednisolone acetate (20 mg SC q 2 weeks), megestrol acetate, hypoallergenic diets, radiation therapy, surgery, immunomodulation, or cryosurgery
  • prognosis: fair for complete and permanent recovery


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