Veterinary Society of
Surgical Oncology

Biologic Behaviour

  • FSA is the 3rd most common primary bone neoplasm (5%-9%)
  • FSA should be differentiated from fibroblastic OSA
  • 30%-40% FSA occur in the appendicular skeleton
  • FSA may be endosteal (common) or parosteal
  • parosteal may represent STS with extension into adjacent bone
  • appendicular FSA is less malignant than oral FSA and slower to metastasize than appendicular OSA
  • pathologic fracture 50%
  • radiographic findings: usually lytic but occasionally can resemble OSA
  • metastatic sites include heart, pericardium, skin, and other bones, but lungs are an uncommon metastatic site
  • treatment: surgical resection is recommended, but role of chemotherapy is unknown
  • 12-month survival rate 29% with limb-sparing surgery and 66% after limb amputation
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