Veterinary Society of
Surgical Oncology

General Considerations

  • malignant tumor of striated muscle
  • signalment: young dogs
  • biologic behaviour: locally invasive with metastasis to lungs, liver, spleen, kidneys, and adrenal gland
  • grape-like appearance has resulted in description of botryoid, particularly in the urinary bladder
  • histology: large, pleomorphic elongated tumor cells (= strap cells) with cross-striation in eosinophilic cytoplasm
  • poor prognostic factors in humans include metastatic disease and poor response to chemotherapy
  • age, location, nodal status, and histologic subtype (i.e., embryonal, botryoid, alveolar or pleomorphic) are not prognostic


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