Veterinary Society of
Surgical Oncology

Trigeminal Nerve Tumor


  • types: nerve sheath (common) and LSA
  • trigeminal nerve sheath tumors tend to be locally invasive with a low metastatic rate
  • trigeminal nerve sheath tumors tend to spread proximally into the central neural axis

Clinical Features

  • trigeminal nerve sheath tumors present with unilateral temporalis and masseter muscle atrophy and unilateral dysfunction of ophthalmic, maxillary ± mandibular branches (i.e., poor or altered sensation around the eyelids and lips with poor blink reflex and wrinkling of face)
  • diagnosis: EMG of masticatory muscles and MRI
  • surgical resection via lateral rostrotentorial craniectomy or trans-zygomatic craniectomy (for ventral access)
  • radiation therapy may be indicated for primary treatment or as an adjunct to surgical resection
  • prognosis: guarded to poor


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