Veterinary Society of
Surgical Oncology

General Considerations

  • calcinosis circumscripta is reported in cats and dogs
  • deposition of calcium in areas other than bone or teeth is pathologic and termed either dystrophic, metastatic, idiopathic, or iatrogenic
  • dystrophic calcification: deposition of calcium salts within dead or degenerative tissue and is unrelated to calcium content of blood
  • metastatic calcification: precipitation of calcium salts within tissue because of derangements in metabolism of calcium, phosphorus, or both (i.e., primary, secondary, and pseudohyperparathyroidism, chronic renal failure, and hypervitaminosis D)
  • calcium deposited as calcium phosphate, calcium carbonate, or as hydroxyapatite
  • calcium circumscripta definition: local ectopic deposition of calcium salts usually in subcutaneous tissue
  • cause unknown although associated with trauma, injections, and previous surgery
  • calcinosis cutis has been secondary to intramuscular injection of calcium gluconate for the management of primary hypoparathyroidism
  • gross appearance: ≥ 1 small, well-circumscribed subcutaneous mass
  • other sites: tongue, salivary gland, spine, and aorta


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