Veterinary Society of
Surgical Oncology

2013

Buishand FO, Kirpensteijn J, Jaarsma AA, Speel EJ, Kik M, Mol JA. Gene expression profiling of primary canine insulinomas and their metastases. Vet J 2013.

Fahey CE, Milner RJ, Kow K, Bacon NJ, Salute ME. Apoptotic effects of the tyrosine kinase inhibitor, masitinib mesylate, on canine osteosarcoma cells. Anticancer Drugs 24:519-526, 2013.

Haagsman AN, Witkamp AC, Sjollema BE, Kik MJ, Kirpensteijn J. The effect of interleukin-2 on canine peripheral nerve sheath tumours after marginal surgical excision: a double-blind randomized study. BMC Vet Res 9:155, 2013.

Maniscalco L, Iussich S, Morello E, Martano M, Biolatti B, Riondato F, Della Salda L, Romanucci M, Malatesta D, Bongiovanni L, Tirrito F, Gattino F, Buracco P, De Maria R. PDGFs and PDGFRs in canine osteosarcoma: new targets for innovative therapeutic strategies in comparative oncology. Vet J 195:41-47, 2013.

Marley K, Helfand SC, Edris WA, Mata JE, Gitelman AI, Medlock J, Séguin B. The effects of taurolidine alone and in combination with doxorubicin or carboplatin in canine osteosarcoma in vitro. BMC Vet Res 9:15, 2013.

Milovancev M, Hilgart-Martiszus I, McNamara MJ, Goodall CP, Séguin B, Bracha S, Wickramasekara SI. Comparative analysis of the surface exposed proteome of two canine osteosarcoma cell lines and normal canine osteoblasts. BMC Vet Res 9:116, 2013.

Selvarajah GT, Bonestroo FA, Kirpensteijn J, Kik MJ, van der Zee R, van Eden W, Timmermans-Sprang EP, Slob A, Mol JA. Heat shock protein expression analysis in canine osteosarcoma reveals HSP60 as a potentially relevant therapeutic target. Cell Stress Chaperones 2013.

Scharf VF, Farese JP, Coomer AR, Milner RJ, Taylor DP, Salute ME, Chang MN, Neal D, Siemann DW. Effect of bevacizumab on angiogenesis and growth of canine osteosarcoma cells xenografted in athymic mice. AJVR 74:771-778, 2013.

Schwartz AL, Custis JT, Harmon JF, Powers BE, Chubb LS, LaRue SM, Ehrhart NP, Ryan SD. Orthotopic model of canine osteosarcoma in athymic rats for evaluation of stereotactic radiotherapy. AJVR 74:452-458, 2013.

Ziekman PG, Otter WD, Tan JF, Teske E, Kirpensteijn J, Koten JW, Jacobs JJ. Intratumoural interleukin-2 therapy can induce regression of non-resectable mastocytoma in dogs. Anticancer Res 33:161-165, 2013.

2012

Bongiovanni L, Mazzocchetti F, Malatesta D, Romanucci M, Ciccarelli A, Buracco P, De Maria R, Palmieri C, Martano M, Morello E, Maniscalco L, Della Salda L. Immunohistochemical investigation of cell cycle and apoptosis regulators (survivin, β-catenin, p53, caspase 3) in canine appendicular osteosarcoma. BMC Vet Res 8:78, 2012.

Buishand FO, van Erp MG, Groenveld HA, Mol JA, Kik M, Robben JH, Kooistra HS, Kirpensteijn J. Expression of insulin-like growth factor-1 by canine insulinomas and their metastases. Vet J 191:334-340, 2012.

Modiano JF, Bellgrau D, Cutter GR, Lana SE, Ehrhart NP, Ehrhart E, Wilke VL, Charles JB, Munson S, Scott MC, Pozniak J, Carlson CS, Schaack J, Duke RC. Inflammation, apoptosis, and necrosis induced by neoadjuvant fas ligand gene therapy improves survival of dogs with spontaneous bone cancer. Mol Ther 20:2234-2243, 2012.

Romanucci M, D'Amato G, Malatesta D, Bongiovanni L, Palmieri C, Ciccarelli A, Buracco P, Morello E, Maniscalco L, De Maria R, Martano M, Della Salda L. Heat shock protein expression in canine osteosarcoma. Cell Stress Chaperones 17:131-138, 2012.

Santoni BG, Ehrhart N, Betancourt-Benitez R, Beck CA, Schwarz EM. Quantifying massive allograft healing of the canine femur in vivo and ex vivo: a pilot study. Clin Orthop Relat Res 470:2478-2487, 2012.

Selvarajah GT, Verheije MH, Kik M, Slob A, Rottier PJ, Mol JA, Kirpensteijn J. Expression of epidermal growth factor receptor in canine osteosarcoma: association with clinicopathological parameters and prognosis. Vet J 193:412-419, 2012.

Walters J, Ryan S, Harmon JF Jr. Characterization of differences in calculated and actual measured skin doses to canine limbs during stereotactic radiosurgery using Gafchromic film. Med Dosim 37:201-207, 2012.

Youmans L, Taylor C, Shin E, Harrell A, Ellis AE, Séguin B, Ji X, Zhao S. Frequent alteration of the tumor suppressor gene APC in sporadic canine colorectal tumors. PLoS One 7:e50813, 2012.

2011

Mayayo SL, Prestigio S, Maniscalco L, La Rosa G, Aricò A, De Maria R, Cavallo F, Ferrone S, Buracco P, Iussich S. Chondroitin sulfate proteoglycan-4: a biomarker and a potential immunotherapeutic target for canine malignant melanoma. Vet J 190:e26-30, 2011.

Woll KA, Schuchardt EJ, Willis CR, Ortengren CD, Hendricks N, Johnson M, Gaidamauskas E, Baruah B, Sostarecz AG, Worley DR, Osborne DW, Crans DC. Gel formulation containing mixed surfactant and lipids associating with carboplatin. Chem Biodivers 8:2195-2210, 2011.

2010

Green N, Boothe DM, Smith A, Henderson R, Whitley E. Ex vivo viability of canine and feline sarcomas: a pilot study. Vet Ther 11:E1-11, 2010.

Roato I, Caldo D, Godio L, D'Amico L, Giannoni P, Morello E, Quarto R, Molfetta L, Buracco P, Mussa A, Ferracini R. Bone invading NSCLC cells produce IL-7: mice model and human histologic data. BMC Cancer 12:12, 2010.

Sottnik JL, U'Ren LW, Thamm DH, Withrow SJ, Dow SW. Chronic bacterial osteomyelitis suppression of tumor growth requires innate immune responses. Cancer Immunol Immunother 59:367-378, 2010.

2009

Fieten H, Spee B, Ijzer J, Kik MJ, Penning LC, Kirpensteijn J. Expression of hepatocyte growth factor and the proto-oncogenic receptor c-Met in canine osteosarcoma. Vet Pathol 46:869-877, 2009.

2008

Coomer AR, Farese JP, Milner R, Taylor D, Salute ME, Rajon DA, Bova FJ, Siemann DW. Development of an intramuscular xenograft model of canine osteosarcoma in mice for evaluation of the effects of radiation therapy. Am J Vet Res 70:127-133, 2009.

De Maria R, Miretti S, Iussich S, Olivero M, Morello E, Bertotti A, Christensen JG, Biolatti B, Levine RA, Buracco P, Di Renzo MF. met oncogene activation qualifies spontaneous canine osteosarcoma as a suitable pre-clinical model of human osteosarcoma. J Pathol. 218:399-408, 2009.

Ehrhart N, Kraft S, Conover D, Rosier RN, Schwarz EM. Quantification of massive allograft healing with dynamic contrast-enhanced MRI and cone beam CT: a pilot study. Clin Orthop Relat Res 466:1897-1904, 2008.

Fitzpatrick CL, Farese JP, Milner RJ, Salute ME, Rajon DA, Morris CG, Bova FJ, Lurie DM, Siemann DW: Intrinsic radiosensitivity and repair of sublethal radiation-induced damage in canine osteosarcoma cell lines. Am J Vet Res 69:1197-1202, 2008.

Kamishina H, Farese JP, Storm JA, Cheeseman JA, Clemmons RM. The frequency, growth kinetics, and osteogenic/adipogenic differentiation properties of canine bone marrow stromal cells. In Vitro Cell Dev Biol Anim 44:472-479, 2008.

Kirpensteijn J, Kik M, Teske E, Rutteman GR. TP53 gene mutations in canine osteosarcoma. Vet Surg 37:454-460, 2008.

Miretti S, Roato I, Taulli R, Ponzetto C, Cilli M, Olivero M, Di Renzo MF, Godio L, Albini A, Buracco P, Ferracini R. A mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by Luciferase imaging. PLoS ONE 19:e1828, 2008.

Santoni BG, Turner AS, Wheeler DL, Nicholas RW, Anchordoquy TJ, Ehrhart N. Gene therapy to enhance allograft incorporation after host tissue irradiation. Clin Orthop Relat Res 466:1921-1929, 2008.

Santoni BG, Ehrhart N, Turner AS, Wheeler DL. Effects of low intensity pulsed ultrasound with and without increased cortical porosity on structural bone allograft incorporation. J Orthop Surg 27:20, 2008.

2007

Cerruti F, Martano M, Petterino C, Bollo E, Morello E, Bruno R, Buracco P, Cascio P. Enhanced expression of interferon-gamma-induced antigen-processing machinery components in a spontaneously occurring cancer. Neoplasia 9:969-969, 2007.

Culp WT, Weisse C, Cole SG, Solomon JA. Intraluminal tracheal stenting for treatment of tracheal narrowing in three cats. Vet Surg 36:107-113, 2007.

Gaines PJ, Powell TD, Walmsley SJ, Estredge KL, Wisnewski N, Stinchcomb DT, Withrow SJ, Lana SE. Identification of serum biomarkers for canine B-cell lymphoma by use of surface-enhanced laser desorption-ionization time-of-flight mass spectrometry. Am J Vet Res 68:405-410, 2007.

Jehn CT, Lewis DD, Farese JP, Ferrell EA, Conley WG, Ehrhart N. Transverse ulnar bone transport osteogenesis: a new technique for limb salvage for the treatment of distal radial osteosarcoma in dogs. Vet Surg 36:324-334, 2007.

MacDiarmid JA, Mugridge NB, Weiss JC, Phillips L, Burn AL, Paulin RP, Haasdyk JE, Dickson KA, Brahmbhatt VN, Pattison ST, James AC, Al Bakri G, Straw RC, Stillman B, Graham RM, Brahmbhatt H. Bacterially derived 400 nm particles for encapsulation and cancer cell targeting of chemotherapeutics. Cancer Cell 11:431-445, 2007

2006

Liptak JM, Ehrhart N, Santoni BG, Wheeler DL. Cortical bone graft and endoprosthesis in the distal radius of dogs: a biomechanical comparison of two different limb-sparing techniques. Vet Surg 35:150-160, 2006.

Milner RJ, Salute M, Crawford C, Abbot JR, Farese J. The immune response to disialoganglioside GD3 vaccination in normal dogs: A melanoma surface antigen vaccine. Vet Immunol Immunopathol 114:273-284, 2006.

Petterino C, Martano M, Cascio P, Cerruti F, Martini M, Morello E, Bruno R, Castagnaro M, Buracco P. Immunohistochemical study of STAT3 expression in feline injection-site fibrosarcomas. J Comp Pathol 134:91-100, 2006

2005

Ashton JA, Farese JP, Milner RJ, Lee-Ambrose LM, van Gilder JM. Investigation of the effect of pamidronate disodium on the in vitro viability of osteosarcoma cells from dogs. Am J Vet Res 66:1961-1967, 2005.

Dewhirst MW, Poulson JM, Yu D, Sanders L, Lora-Michiels M, Vujaskovic Z, Jones EL, Samulski TV, Powers BE, Brizel DM, Prosnitz LR, Charles HC. Relation between pO2, 31P magnetic resonance spectroscopy parameters and treatment outcome in patients with high-grade soft tissue sarcomas treated with thermoradiotherapy. Int J Radiat Oncol Biol Phys 61:480-491, 2005.

Ehrhart NP, Hong L, Morgan AL, Eurell JA, Jamison RD. Effect of transforming growth factor-beta1 on bone regeneration in critical-sized bone defects after irradiation of host tissues. Am J Vet Res 66:1039-1045, 2005.

Ehrhart NP, Eurell JA, Constable PD, Gaddy D, Nicholas RW. The effect of host tissue irradiation on large-segment allograft incorporation. Clin Orthop Relat Res 435:43-51, 2005.

Reimer SB, Séguin B, DeCock HE, Walsh PJ, Kass PH. Evaluation of the effect of routine histologic processing on the size of skin samples obtained from dogs. Am J Vet Res 66:500-505, 2005.

Royals SR, Farese JP, Milner RJ, Lee-Ambrose L, van Gilder J. Investigation of the effects of deracoxib and piroxicam on the in vitro viability of osteosarcoma cells from dogs. Am J Vet Res 66:885-891, 2005.

2004

Cagliero E, Ferracini R, Morello E, Scotlandi K, Manara MC, Buracco P, Comandone A, Baroetto Parisi R, Baldini N. Reversal of multidrug-resistance using Valspodar (PSC 833) and doxorubicin in osteosarcoma. Oncol Rep 12:1023-1031, 2004.

Farese JP, Ashton J, Milner R, Ambrose LL, Van Gilder J. The effect of the bisphosphonate alendronate on viability of canine osteosarcoma cells in vitro. In Vitro Cell Dev Biol Anim 40:113-117, 2004.

Farese JP, Fox LE, Detrisac CJ, Van Gilder JM, Roberts SL, Baldwin JM. Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice. Am J Vet Res 65::659-664, 2004.

Feng L, De Dille A, Jameson VJ, Smith L, Dernell WS, Manning MC. Improved potency of cisplatin by hydrophobic ion pairing. Cancer Chemother Pharmacol 54:441-448, 2004.

Flint AF, Uren L, Legare ME, Withrow SJ, Dernell W, Hanneman WH. Overexpression of the erbB-2 proto-oncogene in canine osteosarcoma cell lines and tumors. Vet Pathol 41:291-296, 2004.

Mullins MN, Lana SE, Dernell WS, Ogilvie GK, Withrow SJ, Ehrhart EJ. Cyclooxygenase-2 expression in canine appendicular osteosarcomas. J Vet Intern Med 18:859-865, 2004.

Pooya HA, Séguin B, Mason DR, Walsh PJ, Taylor KT, Kass PH, Stover SM. Biomechanical comparison of cortical radial graft versus ulnar transposition graft limb-sparing techniques for the distal radial site in dogs. Vet Surg 33:301-308, 2004.

2003

Bianco SR, Sun J, Fosmire SP, Hance K, Padilla ML, Ritt MG, Getzy DM, Duke RC, Withrow SJ, Lana S, Matthiesen DT, Dow SW, Bellgrau D, Cutter GR, Helfand SC, Modiano JF: Enhancing antimelanoma immune responses through apoptosis. Cancer Gene Ther 10:726-736, 2003.

Loukopoulos P, Mungall BA, Straw RC, Thornton JR, Robinson WF: Matrix metalloproteinase-2 and -9 involvement in canine tumors. Vet Pathol 40:382-394, 2003.

2002

Dernell WS, Powers BE, Taatjes DJ, Cogan P, Gaudiano G, Koch TH: Evaluation of the epidoxorubicin--formaldehyde conjugate, epidoxoform, in a mouse mammary carcinoma model. Cancer Invest 20:713-724, 2002.

Ehrhart N, Eurell JA, Tommasini M, Constable PD, Johnson AL, Feretti A: Effect of cisplatin on bone transport osteogenesis in dogs. Am J Vet Res 63:703-711, 2002.

Kirpensteijn J, Timmermans-Sprang EP, van Garderen E, Rutteman GR, Lantinga-van Leeuwen IS, Mol JA: Growth hormone gene expression in canine normal growth plates and spontaneous osteosarcoma. Mol Cell Endocrinol 197:179-185, 2002

Morello E, Dernell WS, Kuntz CA, LaRue SM, Lafferty M, Nelson A, Brekke JH, Mallinckrodt CH, Withrow SJ, Manning MC: Evaluation of cisplatin in combination with a biologic response modifier in a murine mammary carcinoma model. Cancer Invest 20:480-489, 20

2000

Ferracini R, Angelini P, Cagliero E, Linari A, Martano M, Wunder J, Buracco P: MET oncogene aberrant expression in canine osteosarcoma. J Orthop Res 18:253-256, 2000.

Lana SE, Ogilvie GK, Hansen RA, Powers BE, Dernell WS, Withrow SJ: Identification of matrix metalloproteinases in canine neoplastic tissue. Am J Vet Res 61:111-114, 2000.

Leibman NF, Lana SE, Hansen RA, Powers BE, Fettman MJ, Withrow SJ, Ogilvie GK: Identification of matrix metalloproteinases in canine cutaneous mast cell tumors. J Vet Intern Med 14:583-586, 2000. 

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